This study aimed to suggest performance-based fire egress planning at the youth ward in the general hospital. Required Safety Egress Time (RSET) was measured with egress simulation at the individual analysis node, and Allowed Safety Egress Time (ASET) was measured with fire simulation. Fire egress performance was analyzed with the time difference between two measures, and the study found weak egress spaces showing less Allowed Safety Egress Time than Required Safety Egress Time. According to the analysis result, reduction of visibility distance among Life Safety Standard components affected the reduction of fire egress performance. In addition, the study clarified that adult assistant’s egress performance was decreased when youth patient’s egress performance was decreased. For decreasing Required Safety Egress Time, architectural space planning providing additional horizontal escape routes and vertical ones is suggested. For increasing Allowed Safety Egress Time, the installation of equipment and control devices is also suggested.