This study was conducted to explore various influencing factors for adaptation to college life and drop-out prevention of new students in the 2021 academic year of B University. College student Adaptability Test(CAT) was conducted for all first-year students, and the final 1,025 subjects were the final research subjects. Multiple regression analysis was used to analyze the relationship between college adaptability variables and college satisfaction, college adaptability variables and dropout tendency. As a result of the study, academic cohesion, social cohesion, career identity, relationship with professors, emotional support at home, and stability in academic continuity were analyzed as significant factors that increase college satisfaction. Factors affecting the risk of dropping out of freshmen were analyzed. As a result, it was found that the higher the academic integrity, emotional stability, satisfaction with college education, and stability of academic continuity, the other variables except the relationship with the professor, the lower the tendency to dropout. On the other hand, social cohesion, career identity, and educational service satisfaction did not have a significant effect. Based on these results, a university-level plan was proposed to increase the discussion and university satisfaction.